Can I set up a vacation autoresponder for my email account when I am away?
Yes. Office 365 provides an e-mail auto-reply that automatically responds to senders of your incoming e-mail messages with a message notifying them that you are away and/or unable to read your e-mail. This service provided for the campus centralized Office 365 e-mail service accounts.
For additional information, including instructions on how to set up the auto-reply, see the Microsoft Setup Automatic Replies document.